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Seprase Polyclonal Antibody, 20ul Human Genome Knockout Libraries Deletions in this gene may

SKU: 74570994309

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Seprase Polyclonal Antibody, 20ul Human Genome Knockout Libraries Deletions in this gene mayThe fibroblast activation protein alpha encoded by FAP is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. Seprase is thought to be involved in the control of fibroblast growth or epithelial mesenchymal interactions during development, tissue

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Description

Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome

Alternative promoter usage and alternate splicing result in multiple variants encoding different isoforms

The encoded protein (nuclear cap binding protein subunit 2) has an RNP domain commonly found in RNA binding proteins

Defects in this gene can be a cause of Brugada Syndrome

These channels are heteromeric complexes consisting of 3 subunits: alpha

Seprase Polyclonal Antibody, 20ul Human Genome Knockout Libraries Deletions in this gene mayThe fibroblast activation protein alpha encoded by FAP is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. Seprase is thought to be involved in the control of fibroblast growth or epithelial mesenchymal interactions during development, tissue

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