IGF-I Receptor beta(Phospho-Tyr1131) Rabbit Polyclonal Antibody, 20ul Cell Culture Plates subcellular location:Translocates to the cytoplasm

subcellular location:Translocates to the cytoplasm on phosphorylation where it binds binding to YWHAZ

The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain

An important paralog of this gene is SNRNP200

IRX3 is a member of the Iroquois homeobox gene family (see IRX1

and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells

IGF-I Receptor beta(Phospho-Tyr1131) Rabbit Polyclonal Antibody, 20ul Cell Culture Plates subcellular location:Translocates to the cytoplasmThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have