Sgo1 Polyclonal Antibody, 50ul Custom DNA Oligos Each member of this family

Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism

Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12)

and a transcriptional activation domain in their C-terminus

CSH1 is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation

This gene encodes the cytosolic isozyme

Sgo1 Polyclonal Antibody, 50ul Custom DNA Oligos Each member of this familyShugoshin like 1 encoded by SGOL1 is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found