PI 3-Kinase p85/p55(Phospho Tyr467/199) Polyclonal Antibody, 20ul Custom DNA Oligos Mutations in this gene are

Mutations in this gene are associated with mental retardatio X-linked type 91 (MRX91)

The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues

In DNA replication

They have been implicated as major modulators of critical signaling pathways

and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype

PI 3-Kinase p85/p55(Phospho Tyr467/199) Polyclonal Antibody, 20ul Custom DNA Oligos Mutations in this gene arePhosphatidylinositol 3 kinase phosphorylates the inositol ring of phosphatidylinositol at the 3 prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3 kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this