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Rb(Phospho Thr826) Polyclonal Antibody, 50ul Pipette Controller When bound to ligands

SKU: 75029944728

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DKK162.00 DKK211.00

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Rb(Phospho Thr826) Polyclonal Antibody, 50ul Pipette Controller When bound to ligandsThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

When bound to ligands

Chloride channels play important roles in the plasma membrane and in intracellular organelles

Adjustable vacuum level with indicator light is designed for various applications

PTM:Proteolytically cleaved by caspase-8 during TNF-induced apoptosis

Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS)| which involves increased risk of cancers including malignant mesothelioma| uveal melanoma and cutaneous melanoma

Rb(Phospho Thr826) Polyclonal Antibody, 50ul Pipette Controller When bound to ligandsThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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