BAG2 Polyclonal Antibody, 50ul Immune Repertoire Sequencing Both calcium/calmodulin and protein phosphorylation

Both calcium/calmodulin and protein phosphorylation mechanisms control its activity

This gene encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules

tissue specificity:Preferentially detected in breast carcinoma tissue and mammary gland

Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors

Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS)

BAG2 Polyclonal Antibody, 50ul Immune Repertoire Sequencing Both calcium/calmodulin and protein phosphorylationBAG proteins compete with Hip for binding to the Hsc70 Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45 amino acid BAG domain near the C terminus but differ markedly in their N terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high