SREC Polyclonal Antibody, 20ul Capsule Filter It is a mainly cytoplasmic

It is a mainly cytoplasmic protein that can translocate to the cell membrane after cell stimulation

Alternatively spliced transcript variants encoding different isoforms have been observed for this gene

it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties

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The encoded protein (caspase recruitment domain family member 6) is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB

SREC Polyclonal Antibody, 20ul Capsule Filter It is a mainly cytoplasmicThe protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac LDL), and it may be involved in atherogenesis. This gene is regulated by the transcription factors ZNF444 EZF 2 and SP1. Alternative splicing results in multiple transcript variants.