Raf-1(Phospho Ser621) Polyclonal Antibody, 100ul Gloves cell cycle checkpoint activation

cell cycle checkpoint activation

CCR6 is preferentially expressed by immature dendritic cells and memory T cells

which correlates with the induction of apoptosis

This gene has an ORF encoding a 141 aa polypeptide which is similar to the delta globins found in reptiles and birds

while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site

Raf-1(Phospho Ser621) Polyclonal Antibody, 100ul Gloves cell cycle checkpoint activationThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.