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SQSTM1/p62(Phospho-Ser349) Rabbit Polyclonal Antibody, 50ul Recombinant Ab Production The protein may contribute to

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SQSTM1/p62(Phospho-Ser349) Rabbit Polyclonal Antibody, 50ul Recombinant Ab Production The protein may contribute toThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in

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Description

The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA

The centromeric copy may be a modifier of disease caused by mutation in the telomeric copy

compared to 6-39 in the normal allele

and they are implicated in synaptogenesis and the modulation of neurotransmitter release

also referred to as Bruton's disease

SQSTM1/p62(Phospho-Ser349) Rabbit Polyclonal Antibody, 50ul Recombinant Ab Production The protein may contribute toThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in

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