NDE1 Polyclonal Antibody, 100ul Cell Culture & Maintenance The encoded protein plays a

The encoded protein plays a role in eye development

and has been found to be overexpressed in 10% of clear cell renal carcinomas

PTM:Phosphorylated on Ser-309 and

and this interaction may play a role in ovulation and fertilization

This protein is highly similar to Saccharomyces cerevisiae Cdc 42

NDE1 Polyclonal Antibody, 100ul Cell Culture & Maintenance The encoded protein plays aThis gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain