PRAF3 Rabbit Polyclonal Antibody, 100ul Reservoirs NFKB is a transcription regulator

NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines

Alternate splicing results in three transcript variants

and have been shown to be overexpressed in a variety of human cancers

The chaperonin containing TCP1 subunit 5 encoded by CCT5 is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT)

SIAH2 encodes E3 ubiquitin-protein ligase SIAH2 that is a member of the seven in absentia homolog (SIAH) family

PRAF3 Rabbit Polyclonal Antibody, 100ul Reservoirs NFKB is a transcription regulatorExpression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid which results in a specific reduction in EAAC1 mediated glutamate transport.