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IRAK-1(Phospho Ser376) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) Alternative splicing results in multiple

SKU: 75887026773

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IRAK-1(Phospho Ser376) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) Alternative splicing results in multipleThis gene encodes the interleukin 1 receptor associated kinase 1, one of two putative serine threonine kinases that become associated with the interleukin 1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1 induced upregulation of the transcription factor NF kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Description

Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing

One isoform lacks the intermembrane region and is secreted outside the cell

Mutations in this gene are associated with mitochondriopathy and macrocytic anemia

Ephrin A2 is composed of a signal sequence

The protein encoded by this gene belongs to the SMAD family of proteins

IRAK-1(Phospho Ser376) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) Alternative splicing results in multipleThis gene encodes the interleukin 1 receptor associated kinase 1, one of two putative serine threonine kinases that become associated with the interleukin 1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1 induced upregulation of the transcription factor NF kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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