MARCH2 Polyclonal Antibody, 50ul Glassware and peripheral nerve

and peripheral nerve

NPHP4 encodes a protein involved in renal tubular development and function

lacking the N-terminal hydrophobic region but retaining the same activity

suggesting diverse functions in signal transduction

This gene is expressed in kidney and brain

MARCH2 Polyclonal Antibody, 50ul Glassware and peripheral nerveMARCH2 (membrane associated ring CH type finger 2) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome to trans Golgi network (TGN) trafficking.