ARHGEF10 Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection This subunit joins with a

This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family

This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation

Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3)

MLH3 is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes

KLK8 is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19

ARHGEF10 Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection This subunit joins with aARHGEF10 encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in ARHGEF10 are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants.