53BP1 Polyclonal Antibody, 50ul[BT-AP00040] Centrifugal Filter Among its related pathways are

Among its related pathways are Metabolism and Sphingolipid metabolism

Two transcript variants encoding different isoforms have been found for CHGA

Multiple transcript variants encoding different isoforms have been found for PHACTR4

such as IL2

class II and class III

53BP1 Polyclonal Antibody, 50ul[BT-AP00040] Centrifugal Filter Among its related pathways areThe p53 binding proteins 53BP1 and 53BP2 (Bbp) bind to the central DNA binding domain of wild type p53, but do not bind mutant p53. The central DNA binding domain of p53 is required for site specific DNA binding and is frequently mutated in malignant tumors. Binding of 53BP1 to the L3 loop of p53 and of 53BP2 to the L2 loop of p53 confirms that the loop is dependent on p53 conformation. Site specific binding also suggests that 53BP1 and 53BP2 are