DNA-PK(Phospho Thr2609) Rabbit Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) Defects in this gene cause

Defects in this gene cause familial adenomatous polyposis (FAP)

This gene encodes a protein belonging to the 14-3-3 family of proteins| members of which mediate signal transduction by binding to phosphoserine-containing proteins

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Diseases associated with ENPEP include neurogenic hypertension and gestational choriocarcinoma

Its expression is restricted to premeiotic germ cells| particularly in spermatogonia

DNA-PK(Phospho Thr2609) Rabbit Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) Defects in this gene causeCatalytic activity: ATP + a protein = ADP + a phosphoprotein. enzyme regulation: Inhibited by wortmannin. Activity of the enzyme seems to be attenuated by autophosphorylation. Serine threonine protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing