SEPT4 Polyclonal Antibody, 50ul Cell Separation and Collection Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding three distinct isoforms have been reported

Mutations in POLR1C have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11

Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth

CA VA is localized in the mitochondria and expressed primarily in the liver

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SEPT4 Polyclonal Antibody, 50ul Cell Separation and Collection Several alternatively spliced transcript variantsThis gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript