TLX1 Polyclonal Antibody, 100ul Centrifuges The protein encoded by this

The protein encoded by this gene is a regulatory protein involved in mitosis

Three transcript variants encoding different isoforms have been found for CBF2alpha

Cofactors B and E can form a heterodimer which binds to alpha-tubulin and enhances their ability to dissociate tubulin heterodimers

promotes p53/TP53 phosphorylation on ‘Ser-46' and subsequent apoptosis

An important paralog of this gene is RIMKLA

TLX1 Polyclonal Antibody, 100ul Centrifuges The protein encoded by thisThis gene encodes a nuclear transcription factor that belongs to the NK linked or NK like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T cell acute lymphoblastic leukemias. Alternate splicing results in