Ki-67 Monoclonal Antibody, 100ul[BT-MCA0804] Cell Function Analysis Tumor protein p53 responds to

Tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes

and parastatin

This protein contains an actin filament-binding domain| which together with its Dbl homology domain and one of its pleckstrin homology domains| can form microspikes

This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator

and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression

Ki-67 Monoclonal Antibody, 100ul[BT-MCA0804] Cell Function Analysis Tumor protein p53 responds toThis gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X.