ASC-1 Polyclonal Antibody, 50ul Bio-Reaction Tube Mutations in BUB1 have been

Mutations in BUB1 have been associated with aneuploidy and several forms of cancer

Mutations in the human gene are associated with selective tooth agenesis-3

PAK1IP1 also binds to the N-terminus of PAK1

Expression of this gene is associated with a poor prognosis for glioma patients

stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues

ASC-1 Polyclonal Antibody, 50ul Bio-Reaction Tube Mutations in BUB1 have beenTRIP4 (thyroid hormone receptor interactor 4) encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC 1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors mediated transcription. This protein is localized in the nucleus and contains an E1A type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand