LATS1(Phospho-Thr1079) Rabbit Polyclonal Antibody, 50ul Pasteur Pipets Guanine nucleotide-binding proteins (G proteins)

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems

SLC25A11 contains 3 solcar repeats

Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord

The encoded protein is involved in platelet activation and controls the expression of interleukin-2

Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863

LATS1(Phospho-Thr1079) Rabbit Polyclonal Antibody, 50ul Pasteur Pipets Guanine nucleotide-binding proteins (G proteins)The protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity indicating a role as a negative