GSTM5 Rabbit Polyclonal Antibody, 100ul Buffer Solutions Individuals with certain allelic variants

Individuals with certain allelic variants are said to have a poor metabolizer phenotype

The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13

Compact and portable

Multiple alternatively spliced transcript variants have been described for this gene

It is a cytoskeletal protein that interacts with F-actin and Arp2/3 complex and plays an important role in regulation of actin assembly and cytoskeleton dynamics

GSTM5 Rabbit Polyclonal Antibody, 100ul Buffer Solutions Individuals with certain allelic variantsCytosolic and membrane bound forms of glutathione S transferase are encoded by two distinct supergene families. At present eight distinct classes of the soluble cytoplasmic mammalian glutathione S transferases have been identified: alpha kappa mu omega pi sigma theta and zeta. This gene encodes a glutathione S transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds including