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SH3K1 Polyclonal Antibody, 100ul Mechanical Pipette The type I isozyme has

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SH3K1 Polyclonal Antibody, 100ul Mechanical Pipette The type I isozyme hasThis gene encodes an adapter protein that contains three N terminal Src homology domains, a proline rich region and a C terminal coiled coil domain. The encoded protein facilitates protein protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin dependent endocytosis. Alternate splicing results in multiple transcript variants.

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Description

The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities

|Contains 1 CIDE-N domain

Alternative splicing occurs at TNS2 and three transcript variants encoding three distinct isoforms have been identified

The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin

Contributes to cell motility by controlling actin dynamics

SH3K1 Polyclonal Antibody, 100ul Mechanical Pipette The type I isozyme hasThis gene encodes an adapter protein that contains three N terminal Src homology domains, a proline rich region and a C terminal coiled coil domain. The encoded protein facilitates protein protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin dependent endocytosis. Alternate splicing results in multiple transcript variants.

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