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ARL11 Polyclonal Antibody, 20ul Monoclonal Antibodies This gene encodes a member

SKU: 77064469537

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ARL11 Polyclonal Antibody, 20ul Monoclonal Antibodies This gene encodes a memberThis gene encodes a tumor suppressor related to the ADP ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase dependent manner. Polymorphisms in this gene have been associated with some familial cancers.

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Description

This gene encodes a member of the prefoldin beta subunit family

giving rise to several mRNA species

The gene is located in a major X/Y block of homology and its Y homolog| despite divergence leading to coding region changes| is the most closely related cadherin family member

The encoded protein also catalyzes the interconversion of 3-beta-hydroxy- and 3-keto-5-alpha-androstane steroids

These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex

ARL11 Polyclonal Antibody, 20ul Monoclonal Antibodies This gene encodes a memberThis gene encodes a tumor suppressor related to the ADP ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase dependent manner. Polymorphisms in this gene have been associated with some familial cancers.

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