PK1IP Polyclonal Antibody, 20ul ssDNA Synthesis This gene encodes a transcription

This gene encodes a transcription factor that binds the alpha-globin promoter and activates transcription of the alpha-globin gene

The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements

It is secreted into some bodily fluids

tissue specificity:Highly expressed in placenta

Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types

PK1IP Polyclonal Antibody, 20ul ssDNA Synthesis This gene encodes a transcriptionNegatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N terminal regulatory domain. PAK1IP1 also binds to the N terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42.,Contains 5 WD