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MAGE-A5 Polyclonal Antibody, 50ul Human Genome Knockout Libraries May play a role in

SKU: 77166877457

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MAGE-A5 Polyclonal Antibody, 50ul Human Genome Knockout Libraries May play a role inMAGEA5 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary

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Description

May play a role in microtubule nucleation by centrosome

and they activate or interact with various endogenous or exogenous ligands

Two transcripts that encode the same protein have been identified for this gene

A second ligand| the heditary hemochromatosis protein HFE| competes for binding with transferrin for an overlapping C-terminal binding site

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MAGE-A5 Polyclonal Antibody, 50ul Human Genome Knockout Libraries May play a role inMAGEA5 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary

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