EHMT2 Polyclonal Antibody, 50ul Cellular Function Assays Breast cancer metastasis-suppressor 1 encoded

Breast cancer metastasis-suppressor 1 encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC)

which plays an important role in maintenance of muscle structure and function

|PTM:The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells

Mutations in ATP7A are associated with Menkes disease

Several transcript variants are resulted from alternative splicing of SIRT2

EHMT2 Polyclonal Antibody, 50ul Cellular Function Assays Breast cancer metastasis-suppressor 1 encodedThis gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants.