Porcine Clusterin, CLU ELISA Kit, 96T CellSafe™ Plays an important role in

Plays an important role in podosome formation and associated function

Mutations in this gene may be associated with reduced bone mineral density (BMD)

which are implicated in actin remodeling

Required for normal spermatogenesis (PubMed: 1770140

Plays a role in receptor-mediated endocytosis via clathrin-coated pits (By similarity)

Porcine Clusterin, CLU ELISA Kit, 96T CellSafe™ Plays an important role inFunctions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8 HSC70. Does not refold proteins by