p47-phox Polyclonal Antibody, 50ul[BT-AP06794] Shakers It has tyrosine kinase activity

It has tyrosine kinase activity

This kinase undergoes autophosphorylation

May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair

but the biological validity of only two has been determined

Overexpression of this gene has been observed in many tumors| which results in chromosome instability| and thus may contribute to tumorigenesis

p47-phox Polyclonal Antibody, 50ul[BT-AP06794] Shakers It has tyrosine kinase activityThe protein encoded by NCF1 (neutrophil cytosolic factor 1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in NCF1 have been associated with chronic granulomatous disease.