StARD13 Polyclonal Antibody, 100ul Vortex Mixer A novel segment-polarity gene known

A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling

Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia

It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family

A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases

and are postulated to function as brain-specific chemokines or neurokines that act as regulators of immune and nervous cells

StARD13 Polyclonal Antibody, 100ul Vortex Mixer A novel segment-polarity gene knownSTARD13 (StAR related lipid transfer domain containing 13) encodes a protein which contains an N terminal sterile alpha motif (SAM) for protein protein interactions, followed by an ATP GTP binding motif, a GTPase activating protein (GAP) domain, and a C terminal STAR related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma