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NPC1 Rabbit Polyclonal Antibody, 100ul Peptide Library a novel family that links

SKU: 77470519739

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NPC1 Rabbit Polyclonal Antibody, 100ul Peptide Library a novel family that linksThis gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N terminal domain. It is predicted to have a cytoplasmic C terminus 13 transmembrane domains and 3 large loops in the lumen of the endosome the last loop being at the N terminus. This protein transports low density lipoproteins to late endosomal lysosomal compartments

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Description

a novel family that links the chemokine and the transmembrane 4 superfamilies of signaling molecules

In mice and rats

the short isoform(14 kDa) has been shown to repress gamma-globin gene expression

Studies in mice and human suggest that STEAP4 maybe involved in adipocyte development and metabolism

CARD14 (caspase recruitment domain family member 14) encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins

NPC1 Rabbit Polyclonal Antibody, 100ul Peptide Library a novel family that linksThis gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N terminal domain. It is predicted to have a cytoplasmic C terminus 13 transmembrane domains and 3 large loops in the lumen of the endosome the last loop being at the N terminus. This protein transports low density lipoproteins to late endosomal lysosomal compartments

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