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Phospho-B23 (T234) Polyclonal Antibody, 20ul Transporters G1/S-phase cyclin E-cdk2

SKU: 77685333304

4.6
EUR111.00 EUR150.00

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Phospho-B23 (T234) Polyclonal Antibody, 20ul Transporters G1/S-phase cyclin E-cdk2NPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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Description

G1/S-phase cyclin E-cdk2

and insufficient production of the gene may disrupt normal embryonic development

Male mice which lack TSSK6 encoding a highly similar protein are sterile and have morphologically abnormal sperm

a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage

and Liddle syndrome

Phospho-B23 (T234) Polyclonal Antibody, 20ul Transporters G1/S-phase cyclin E-cdk2NPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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