Nibrin Polyclonal Antibody, 20ul[BT-AP06022] Centrifugal Filter The protein localizes to cell

The protein localizes to cell membranes

We propose that human ACBD6 represents a cellular marker for primitive progenitor cells with functions in hematopoiesis and vascular endothelium development

but their full-length natures have not been determined

CHRNA1 encodes an alpha subunit that plays a role in acetlycholine binding/channel gating

Involved in protein trafficking

Nibrin Polyclonal Antibody, 20ul[BT-AP06022] Centrifugal Filter The protein localizes to cellMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.