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Tuberin Polyclonal Antibody, 50ul[BT-AP09287] Cell Function Analysis The lymphotoxin-alpha

SKU: 77740065837

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Tuberin Polyclonal Antibody, 50ul[BT-AP09287] Cell Function Analysis The lymphotoxin-alphaMutations in TSC2 lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

The lymphotoxin-alpha

PTM:Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding

NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells

This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development

The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor

Tuberin Polyclonal Antibody, 50ul[BT-AP09287] Cell Function Analysis The lymphotoxin-alphaMutations in TSC2 lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

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