MMP19 (Cleaved-Tyr98) Rabbit Polyclonal Antibody, 100ul Molecular Biology Alternate splicing results in multiple

Alternate splicing results in multiple transcript variants of this gene

This protein has strong similarity to Mus musculus and Cricetulus griseus proteins

The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route

plays a role in centriole engagement and microtubule nucleation

Beta defensin genes are found in several clusters throughout the genome| with this gene mapping to a cluster at 20p13

MMP19 (Cleaved-Tyr98) Rabbit Polyclonal Antibody, 100ul Molecular Biology Alternate splicing results in multiplealternative products: Additional isoforms seem to exist Catalytic activity: Cleaves aggrecan at the 360 Ser Phe 361 site. cofactor: Binds 1 zinc ion per subunit. cofactor: Calcium. disease: May play a role in pathological processes participating in rheumatoid arthritis (RA) associated joint tissue destruction. Autoantigen anti MMP19 are frequent in RA patients. The conserved cysteine present in the cysteine switch motif binds the catalytic zinc ion