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IP3R-I Polyclonal Antibody, 100ul[BT-AP04603] Dry Bath This intronless gene TSSK6 (testis

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IP3R-I Polyclonal Antibody, 100ul[BT-AP04603] Dry Bath This intronless gene TSSK6 (testisITPR1 (inositol 1,4,5 trisphosphate receptor type 1) encodes an intracellular receptor for inositol 1,4,5 trisphosphate. Upon stimulation by inositol 1,4,5 trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in ITPR1 cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for ITPR1.

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Description

This intronless gene TSSK6 (testis specific serine kinase 6) encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family

including those involved in energy metabolism

NBPF5 (neuroblastoma breakpoint family member 5) is a 351 amino acid cytoplasmic protein that is expressed in medulla and brain and belongs to the NBPF family

Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent

A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases

IP3R-I Polyclonal Antibody, 100ul[BT-AP04603] Dry Bath This intronless gene TSSK6 (testisITPR1 (inositol 1,4,5 trisphosphate receptor type 1) encodes an intracellular receptor for inositol 1,4,5 trisphosphate. Upon stimulation by inositol 1,4,5 trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in ITPR1 cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for ITPR1.

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