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Smad5 Polyclonal Antibody, 50ul Lysosome Component of the probable ECS(LRRC41)

SKU: 78027501537

4.3
USD162.00 USD202.00

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Smad5 Polyclonal Antibody, 50ul Lysosome Component of the probable ECS(LRRC41)Mothers against decapentaplegic homolog 5 encoded by SMAD5 is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.

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Description

Component of the probable ECS(LRRC41) complex with the substrate recognition component LRRC41

CGGBP1 (CGG triplet repeat binding protein 1) influences expression of the FMR1 gene (MIM 309550)

and genital development

At least one additional MEF2B variant and isoform can be expressed from a downstream promoter

The protein encoded by this gene is a Rab-GTPase-activating protein| and contains two phopshotyrosine-binding domains (PTB1 and PTB2)| a calmodulin-binding domain (CBD)| a Rab-GTPase domain| and multiple AKT phosphomotifs

Smad5 Polyclonal Antibody, 50ul Lysosome Component of the probable ECS(LRRC41)Mothers against decapentaplegic homolog 5 encoded by SMAD5 is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.

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