MITF Polyclonal Antibody, 100ul Inoculating Loops/Needles A pseudogene has been identified

A pseudogene has been identified on chromosome 4

a transcription factor which regulates the expression of several hepatic genes

Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12)

The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily

Polymorphisms in this gene have been associated with Alzheimer's disease

MITF Polyclonal Antibody, 100ul Inoculating Loops/Needles A pseudogene has been identifiedMITF encodes microphthalmia associated transcription factor that contains both basic helix loop helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz