Shc(Phospho Tyr427) Polyclonal Antibody, 50ul Cell Culture Flasks This kinase specifically activates MAPK8/JNK1

This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2

5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway

These receptors are composed of an N-terminal glycosylated ligand-binding domain

is amplified in the mouse transformed 3T3 cell line

specifically the homologous recombination pathway for double-strand DNA repair

Shc(Phospho Tyr427) Polyclonal Antibody, 50ul Cell Culture Flasks This kinase specifically activates MAPK8/JNK1This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation.