M4K2 Polyclonal Antibody, 20ul Peptide Library C18orf8 encodes a colon cancer

C18orf8 encodes a colon cancer associated protein

Mutations in this gene are a cause of autosomal recessive spinocerebellar ataxia-11 (SCAR11)

lung and placenta

The encoded protein is required for completion of the mitotic cycle and for targeting protein phosphatase-1 to mitotic kinetochores

alternative products:A number of isoforms

M4K2 Polyclonal Antibody, 20ul Peptide Library C18orf8 encodes a colon cancerThe protein encoded by this gene is a member of the serine threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B cell differentiation. This kinase can be activated by TNF alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor associated factor 2