Rat Rho-associated Protein Kinase 1, ROCK1 ELISA Kit, 96T Deep Well Plates Deacetylates histone H3K9Ac at NF-kappa-B

Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes

With 30 rxns and a concentration of 1 rxn/μl

plays a role in neuronal secretion of specialized preresolving mediators (SPMs) 15R-lipoxin A4 that regulates phagocytic microglia (By similarity)

is essential for development and survival of mast cells in vivo (PubMed: 22438059)

similarity:Contains 3 C2H2-type zinc fingers

Rat Rho-associated Protein Kinase 1, ROCK1 ELISA Kit, 96T Deep Well Plates Deacetylates histone H3K9Ac at NF-kappa-BProtein kinase which is a key regulator of the actin cytoskeleton and cell polarity (PubMed: 19131646, PubMed: 9353125). Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9 MLC2, TPPP, PFN1 and PPP1R12A (PubMed: 19131646, PubMed: 9353125). Phosphorylates FHOD1 and acts