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The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas

Plays an important role in tumor suppression through p53/TP53 regulation

and plays a role in selenium metabolism and protection against oxidative stress

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AATC Polyclonal Antibody, 100ul[BT-AP05896] Apoptosis & Autophagy Dare to take the easyGlutamic oxaloacetic transaminase is a pyridoxal phosphate dependent enzyme which exists in cytoplasmic and mitochondrial forms GOT1 and GOT2 respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.