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MYH6/MYH7 Polyclonal Antibody, 100ul Multiplex Immunoassays Alternate splicing results in coding

SKU: 78447224844

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MYH6/MYH7 Polyclonal Antibody, 100ul Multiplex Immunoassays Alternate splicing results in codingCardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located ~4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.

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Description

Alternate splicing results in coding and non-coding transcript variants

based on its high level of expression in saliva

although for many of them the full-length transcript has not been determined or they are found only in tumor tissues

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer

and is therefore a potential candidate gene for this disorder

MYH6/MYH7 Polyclonal Antibody, 100ul Multiplex Immunoassays Alternate splicing results in codingCardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located ~4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.

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