IGFBP1 Polyclonal Antibody, 20ul[BT-AP04386] Protein Post-translational Modification Several transcript variants encoding different

Several transcript variants encoding different isoforms have been found for this gene

A translocation of POU4F1 is associated with some adult acute myeloid leukemias

Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers

also known as MCLC (Mid-1-related chloride channel) or KIAA0761

for the liver- and erythocyte-specific isoforms

IGFBP1 Polyclonal Antibody, 20ul[BT-AP04386] Protein Post-translational Modification Several transcript variants encoding differentIGFBP1 is a member of the insulin like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type I domain. The protein binds both insulin like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half life of the IGFs and alters their interaction with cell surface receptors.