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TPR Rabbit Polyclonal Antibody, 100ul Tubes The N-terminal nucleotide phosphate binding

SKU: 78457456934

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TPR Rabbit Polyclonal Antibody, 100ul Tubes The N-terminal nucleotide phosphate bindingThis gene encodes a large coiled coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.

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Description

The N-terminal nucleotide phosphate binding region cAMP 1 has a much lower affinity for cAMP as compared to cAMP 2

E2F transcription factor 6 encoded by E2F6 lacks the transactivation and tumor suppressor protein association domains found in other family members

This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development

subthalamic nucleus

Restricted to somata of cerebellar as well as hippocampal neurons

TPR Rabbit Polyclonal Antibody, 100ul Tubes The N-terminal nucleotide phosphate bindingThis gene encodes a large coiled coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.

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