ARL11 Polyclonal Antibody, 100ul Serum an Src-type non-receptor tyrosine kinase

an Src-type non-receptor tyrosine kinase

Present in 80% of breast cancers

Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus

Alternative splicing and the use of alternative promoters results in multiple transcript variants

The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product

ARL11 Polyclonal Antibody, 100ul Serum an Src-type non-receptor tyrosine kinaseThis gene encodes a tumor suppressor related to the ADP ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase dependent manner. Polymorphisms in this gene have been associated with some familial cancers.