JAM-B Polyclonal Antibody, 50ul Proteases May be a tumor suppressor

May be a tumor suppressor in brain cancers

Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome

It has an N-terminal short-chain dehydrogenase domain with a cofactor binding site

It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes

Alternatively spliced transcript variants have been described| but their biological validity has not been determined

JAM-B Polyclonal Antibody, 50ul Proteases May be a tumor suppressorJAM2 belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. Junctional adhesion molecule B encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript