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KPYR Polyclonal Antibody, 100ul RNA Synthesis This protein binds F-actin| and

SKU: 78724054690

4.1
EUR141.00 EUR186.00

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KPYR Polyclonal Antibody, 100ul RNA Synthesis This protein binds F-actin| andThe protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

This protein binds F-actin| and also interacts with 5-lipoxygenase| which is the first committed enzyme in leukotriene biosynthesis

the mature protein translocates to the nucleus and activates transcription by binding to the SRE1

This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family

Chromodomain Y-like protein (CDYL) is a related ubiquitous nuclear protein expressed at moderate levels in most tissues

two TUDOR domains

KPYR Polyclonal Antibody, 100ul RNA Synthesis This protein binds F-actin| andThe protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.

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