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Ob-R Polyclonal Antibody, 50ul[BT-AP06324] Bio-Reaction Tube and the gene that encodes

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Ob-R Polyclonal Antibody, 50ul[BT-AP06324] Bio-Reaction Tube and the gene that encodesThe protein encoded by LEPR belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with

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Description

and the gene that encodes it maps to human chromosome 17q25

The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues

The protein encoded by this gene is similar in sequence to tubulointerstitial nephritis antigen| a secreted glycoprotein that is recognized by antibodies in some types of immune-related tubulointerstitial nephritis

The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity

The N-end rule pathway is one proteolytic pathway of the ubiquitin system

Ob-R Polyclonal Antibody, 50ul[BT-AP06324] Bio-Reaction Tube and the gene that encodesThe protein encoded by LEPR belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with

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