SREK1 Polyclonal Antibody, 50ul Electronic Pipette The N-terminal region of the

The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity

The functional enzyme is thought to be a homodimer which uses FAD as a cofactor

Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis

the full-length nature is known for some but not all of the variants

This gene is highly expressed in testis and the protein is localized to the nucleus

SREK1 Polyclonal Antibody, 50ul Electronic Pipette The N-terminal region of theThis gene encodes a member of a family of serine arginine rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.